|
|
Journal of Basic Research in Medical Sciences، جلد ۴، شماره ۱، صفحات ۸-۱۶
|
|
|
| عنوان فارسی |
|
|
| چکیده فارسی مقاله |
|
|
| کلیدواژه‌های فارسی مقاله |
|
|
| عنوان انگلیسی |
Effect of endurance exercise training on morphological changes in rat heart tissue following experimental myocardial infarction |
|
| چکیده انگلیسی مقاله |
Introduction: Cardiac remodeling after myocardial infarction, is associated with progressive ventricular dysfunction and cardiovascular death. The purpose of this study was to examine the effect of endurance exercise training on morphological changes in rat heart tissue following experimental myocardial infarction. Materials and methods: Rats used in this experiment (8-10 weeks old, 235 ± 5 g body weight) after homogenization according to body weight, were randomly divided to three groups: Healthy (Sham), control (Sedentary) and endurance training groups. Myocardial infarction was induced by subcutaneous injection of isoprenaline (150 mg/kg) in two consecutive days with an interval of 24 hours. Endurance training initiated 2 days after infarction and continued for 4 weeks. In order to assess the necrosis lesion and fibrosis tissue, Hematoxylin–Eosin and Masson's trichrome staining were used, respectively. Data were analyzed by using one-way analysis of variance (ANOVA) at P< 0.05 level. Results: The results indicated that subcutaneous injection of isoprenaline, induced myocardial infarction in rat heart tissue. Rate of necrotic lesion in the Endurance training group was significantly higher than Sedentary (control) group (P=0.005). Also, the size of fibrosis tissue in the Endurance training group was significantly higher than the sedentary (control) group (P= 0.001). Conclusion: In general, results of this study showed that 4 weeks of endurance exercise training after myocardial infarction exacerbate tissue injury in rat heart. |
|
| کلیدواژه‌های انگلیسی مقاله |
|
|
| نویسندگان مقاله |
اکبر اعظمیان جزی | akbar azamian jazi
department of exercise physiology, faculty of literature and human sciences, shahrekord university, shahrekord, iran
هادی عبدی | hadi abdi
department of physical education, payam-e-noor university, tehran, iran
محمدرضا حافظی احمدی | mohammad reza haffezi ahmadi
2. department of pathobiology, faculty of medicine, ilam university of medical science, ilam, iran
سازمان اصلی تایید شده: دانشگاه ایلام (Ilam university)
جواد چراغی | javad cheraghi
3. department of physiology, faculty of veterinary medicine, ilam university, ilam, iran
سازمان اصلی تایید شده: دانشگاه ایلام (Ilam university)
|
|
| نشانی اینترنتی |
http://jbrms.medilam.ac.ir/browse.php?a_code=A-10-142-1&slc_lang=en&sid=en |
| فایل مقاله |
فایلی برای مقاله ذخیره نشده است |
| کد مقاله (doi) |
|
| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Cardiovascular Diseases |
| نوع مقاله منتشر شده |
پژوهشی |
|
|
|
برگشت به:
صفحه اول پایگاه |
نسخه مرتبط |
نشریه مرتبط |
فهرست نشریات
|