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Journal of Basic Research in Medical Sciences، جلد ۳، شماره ۴، صفحات ۳۴-۳۹
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عنوان فارسی |
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چکیده فارسی مقاله |
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کلیدواژههای فارسی مقاله |
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عنوان انگلیسی |
Effect of different concentrations of Aloe vera leave's extract on the healing process of rat's second degree burn |
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چکیده انگلیسی مقاله |
Introduction: The aim of this work was to evaluate the effects of four different concentrations of Aloe vera extract on healing of second degree burns in male Wistar rats. Materials and methods: By an experimental study 42 male Wistar rats were divided into 7 equal groups. The burn injury was made on the back of all rats, according to standard methods. The burned areas in the group1: were left without any intervention, group 2: were treated topically with eucerin, group 3: were treated with SSD and groups 4-7 were covered with 0.5%, 1%, 1.5%, 2% Aloe vera extract in eucerin (basal cream) twice a day, respectively. 21 days later the rats were sacrificed and samples of burnt skin tissue were collected for histological examinations. The parameters were evaluated to be considered for review included the number of hair follicles, sebaceous glands of angiogenesis, acute inflammation (severe infiltration of neutrophils) and the formation of epithelial layers. Results: Diagram of healing levels and reduction rats of wounds' sizes in 3th week indicated that the former was reduced more significantly in groups 3, 6 and 7 than in groups 1 (P< 0.005) and 2 (P< 0.01). Histological findings showed that burn healing was significantly better in groups 6 and 7 than the groups 1 and 2 at the day 21. Conclusion: It could be concluded that concentration of 1.5% and 2% of Aloe vera extract have an effective role in the treatment of burn wound healing. |
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کلیدواژههای انگلیسی مقاله |
Aloe vera, SSD, Second degree burn |
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نویسندگان مقاله |
kholoud ramz | kholoud ramz department of anatomy, faculty of medicine, ilam university of medical sciences, ilam, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایلام (Ilam university of medical sciences)
ناصر عباسی | naser abbasi department of anatomy, faculty of medicine, ilam university of medical sciences, ilam, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایلام (Ilam university of medical sciences)
محمدرضا حافظی احمدی | mohammadreza hafeziahmadi department of pharmacology, faculty of medicine, ilam university of medical sciences, ilam, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایلام (Ilam university of medical sciences)
منیره عزیزی | monireh azizi department of pathology,faculty of medicine, ilam university of medical sciences. ilam. iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایلام (Ilam university of medical sciences)
عظیم هدایت پور | azim hedayatpour department of anatomy, faculty of medicine, ilam university of medical sciences, ilam, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایلام (Ilam university of medical sciences)
حجت اله عباس زاده | hojjatallah abbaszadeh department of anatomy, faculty of medicine, tehran university of medical sciences, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
اردشیر معیری | ardeshir moayeri department ofbiology and anatomical sciences, school of medicine, shahid beheshti university of medical sciences
سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)
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نشانی اینترنتی |
http://jbrms.medilam.ac.ir/browse.php?a_code=A-10-65-4&slc_lang=en&sid=en |
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کد مقاله (doi) |
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زبان مقاله منتشر شده |
en |
موضوعات مقاله منتشر شده |
Medical Anatomy |
نوع مقاله منتشر شده |
پژوهشی |
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