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Journal of Basic Research in Medical Sciences، جلد ۱، شماره ۱، صفحات ۱-۷
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| عنوان انگلیسی |
Investigating antimicrobial activity of hydroalcoholic extract and essential oil of Tymbra spicata against some pathogenic bacteria |
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| چکیده انگلیسی مقاله |
Introduction: Thymbra spicata (T. spicata) is a conventional medicinal herb which is commonly used in the folklore medicine system of Iran. Aim of the study was to assess the antibacterial activity of the essential oil and hudroalcholic extract of the plant T. spicata on some important bacteria. Materials & methods: The essential oil and extract of T. spicata were obtained by hydrodistillation and hydroalcoholic methods, respectively. Different concentrations of essential oil and hydroalcholic extract of the medicinal herb, T. spicata, were evaluated for their antibacterial activities against ten pathogenic bacteria (4 Gram-positive and 6 Gram-negative) by agar disc diffusion and macro Broth dilution method Results: All the bacteria showed a profound susceptibility to the essential oil and hydroalcholic extracts of the T. spicata. The essential oil was shown to be more effective against the examined bacteria. The zone of inhibition of the essential oil shown to be maximum against E. faecalis (28 mm) and M. morganii (30 mm). The hydroalcholic extract of T. spicata, showed the highest antibacterial activity against S. aureus (Gram-positive) and E. coli (Gram-negative) with the zone of inhibitions, 19 mm and 15 mm, respectively. The minimum inhibitory concentration (MIC) values for the essential oil and hydroalcholic extracts ranged from 7-60μg/ mL and 5-19 mg/ml, respectively against the tested bacteria. Conclusion: This study revealed the potential using of T. spicata as a source of antibacterial agents that could be effectively used for medicinal and pharmaceutical purposes. |
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| نویسندگان مقاله |
سالار بختیاری | salar bakhtiyari
ilam university of medical sciences
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایلام (Ilam university of medical sciences)
سمیه سبزعلی | somaieh sabzali
ilam university of medical sciences
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایلام (Ilam university of medical sciences)
آرمان رستم زاد | arman rostamzad
ilam university of medical sciences
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایلام (Ilam university of medical sciences)
غلام بساطی | gholam basati
ilam university of medical sciences
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایلام (Ilam university of medical sciences)
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| نشانی اینترنتی |
http://jbrms.medilam.ac.ir/browse.php?a_code=A-10-26-1&slc_lang=en&sid=en |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Clinical microbiology |
| نوع مقاله منتشر شده |
پژوهشی |
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