Plant Biotechnology Persa، جلد ۷، شماره ۳، صفحات ۰-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Evaluation of Anti-Psoriatic Activity of Aloe sinkatana Extract on Imiquimod Induced Psoriatic-Like Dermatitis in Mice
چکیده انگلیسی مقاله Objectives: One of the most significant Sudanese medicinal plants is Aloe sinkatana, which has a high pharmacological activity and is historically used to treat psoriasis and other skin conditions. This study aims to evaluate the Aloe sinkatana plant's anti-psoratic properties.
Methods: The Imiquimod-induced psoriasis mice model was used to evaluate to the antipsoriatic effect of the Aloe sinkatana plant; the effects of 0.1% & 0.2% extracts of Aloe sinkatana extract on five groups of mice were used, and compared with the conventional medication Dexamethasone  
Results: The extracts showed a significant and remarkably strong anti-psoriatic effect since the percentage of psoriasis-like symptoms was reduced in groups treated with 0.2% Aloe extract, 0.1% Aloe extract & dexamethasone, was 86%, 84%, and 68%, respectively. Both extract concentrations also improved the psoriatic lesions and decreased the grading of the treated groups' psoriasis area and severity index (PASI) scale.
Conclusion: Due to the constant research to develop a safe and effective topical preparation for the treatment of psoriasis, the current study provided an enhanced anti-psoriatic treatment, represented by Aloe sinkatana extract and it may be beneficial in the pharmaceutical formulation of new safe and effective medication for the treatment of psoriasis.
""
 
کلیدواژه‌های انگلیسی مقاله Aloe sinkatana,Dermatitis,Extracts,Imiquimod,psoriasis area and severity index (PASI),Mice
نویسندگان مقاله | Azza Dawoud
Assistant professor


| sali Dawoud
assistant professor


| Mohammed Abdalbagi
Mr..
نشانی اینترنتی http://pbp.medilam.ac.ir/browse.php?a_code=A-10-1496-3&slc_lang=en&sid=1
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Herbal Drugs
نوع مقاله منتشر شده پژوهشی
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات