چکیده انگلیسی مقاله |
Introduction: Neurotransmitters and PGC1α enhance neurological disorders, regulate mitochondrial function, and oxidative stress in the central nervous system, while toxic cadmium damages nervous system structures. In the present study, the effect of eight weeks of high-intensity interval training combined with pollen consumption on the levels of serotonin, dopamine, and PGC-1α proteins in the hippocampus of rats exposed to cadmium was investigated. Materials & Methods: The study involved 25 Sprague-Dawley rats, randomly divided into groups based on their health status, exposure to cadmium, pollen, high-intensity interval training, and pollen+high-intensity interval training. The rats were fed pollen and cadmium chloride daily. Data analysis was conducted using SPSS V.26, two-way variance test, independent t-test, and Mann-Whitney test at a significance level of 0.05. Results: Cadmium levels in the healthy control group were significantly lower than in the others (P=0.001). Also, a significant decrease in cadmium levels was observed in the exercise+pollen group compared to the cadmiump (P=0.031). However, these changes were insignificant compared to the pollen and exercisep (p < 0.05). The main and interaction effects of high-intensity interval training and pollen were not significant for serotonin, dopamine, and PGC-1α levels (p > 0.05). In the pollen, exercise, and pollen+exercise groups, there was no significant difference compared to the cadmium group for serotonin, dopamine, and PGC-1α levels (p>0.05). Conclusion: High-intensity interval training and eating pollen, either separately or together, did not significantly raise the levels of serotonin, dopamine, and PGC-1α proteins in rats that were exposed to cadmium. |
نویسندگان مقاله |
عارف حیدری | Aref Heydari Dept of Exercise Physiology, Bo. C., Islamic Azad University, Borujerd, Iran گروه تربیت بدنی، واحد بروجرد، دانشگاه آزاد اسلامی، بروجرد، ایران
وحید ولی پور ده نو | Vahid Valipour Dehnou Sports Sciences Dept, Faculty of Literature and Human Sciences, Lorestan University, Khorramabad, Iran گروه علوم ورزشی، دانشکده ادبیات و علوم انسانی،دانشگاه لرستان، خرم آباد، ایران
فیروز شرفی دهرحم | Firuz Sharafi Deharham Dept of Physical Education and Sports Sciences, Khor. C., Islamic Azad Univercity, Khorramabad, Iran گروه تربیت بدنی و علوم ورزشی، واحد خرم آباد، دانشگاه آزاد اسلامی، خرم آباد، ایران
مهدی روزبهانی | Mehdi Roozbahani Dept of Motor Behavior, Bo. C., Islamic Azad University, Borujerd, Iran گروه رفتار حرکتی، واحد بروجرد، دانشگاه آزاد اسلامی، بروجرد، ایران
|