|
Journal of Basic Research in Medical Sciences، جلد ۱۲، شماره ۴، صفحات ۱۲-۱۹
|
|
|
عنوان فارسی |
|
|
چکیده فارسی مقاله |
|
|
کلیدواژههای فارسی مقاله |
|
|
عنوان انگلیسی |
Risk Factors Associated with Overall Survival of Breast Cancer Patients Using Multivariate Cox Extended Models |
|
چکیده انگلیسی مقاله |
Introduction: The present study aimed at identifying the risk factors associated with overall survival (OS) of breast cancer (BC) patients using multivariate Cox extended models. Materials & Methods: This retrospective cohort study was conducted on 348 women with BC who were followed up for 10 years. Kaplan-Meier (KM) and log-rank statistics, Cox proportional hazard (PH), and multivariate Cox models were used to analyze the data. STATA V.17 and SPSS V.27 were used for data analysis. Results: The median age of the patients was 55 years, and the median survival time was 29 months. Five- and 10-year OS were estimated at 93.4% and 88.4%, respectively. The results of multivariate analysis using the Cox model showed that lymph node (LN+) (hazard ratio (HR) = 2.86, P = 0.002), tumor size (HR = 1.99, P = 0.001), and progesterone receptor (PR-) (HR = 4.5, P = 0.002) increase death hazard significantly. Conclusion: Prognostic factors indicated that women with lymph node involvement (LN+), positivity of human epidermal growth factor receptor 2 (HER2+), negativity of estrogen receptor (ER-), negative expression of progesterone receptor (PR-), advanced disease grade, and large tumor sizes were more likely to have a high hazard of death than other women. |
|
کلیدواژههای انگلیسی مقاله |
Breast Cancer, Overall survival, Cox extended models |
|
نویسندگان مقاله |
| Khadijeh Mamashli Health faculty, Biostatistics Department, Ilam University of Medical Sciences, Ilam, Iran
| Hassan Nourmohammadi Medicine Faculty, Ilam University of Medical Sciences, Ilam, Iran
| Kourosh Sayehmiri Health faculty, Biostatistics Department, Ilam University of Medical Sciences, Ilam, Iran
|
|
نشانی اینترنتی |
http://jbrms.medilam.ac.ir/browse.php?a_code=A-10-804-2&slc_lang=en&sid=1 |
فایل مقاله |
فایلی برای مقاله ذخیره نشده است |
کد مقاله (doi) |
|
زبان مقاله منتشر شده |
en |
موضوعات مقاله منتشر شده |
Biostatistics |
نوع مقاله منتشر شده |
پژوهشی |
|
|
برگشت به:
صفحه اول پایگاه |
نسخه مرتبط |
نشریه مرتبط |
فهرست نشریات
|